Thorne 5-MTHF 5 mg methylfolate 60 capsules bottle with teal abstract design on white label
Thorne 5-MTHF 5 mg methylfolate 60 capsules bottle with teal abstract design on white labelThorne 5-MTHF 60 Capsules usage guide with a single white capsule and size shown as .563 in / 14.3 mmThorne 5-MTHF 60 Capsules supplement facts label showing folate (L-5-Methyltetrahydrofolate) dosage and other ingredientsThorne 5-MTHF 60 Capsules bottle back showing usage directions, gluten free icon, and manufacturing details on white labelThorne 5-MTHF 60 Capsules bottle back showing supplement facts and ingredient list on white label

Vitamin

Thorne 5-MTHF 5 mg – Methylated Folate, 60 Capsules

Root Cost Meds makes product pricing available to registered account holders on our private membership platform. Certain manufacturers regulate when and how exact product prices may be displayed. Log in to view pricing →

Overview

Thorne 5-MTHF delivers 5 mg of 5-methyltetrahydrofolate, the biologically active form of folate that bypasses common MTHFR genetic variations. Unlike synthetic folic acid, 5-MTHF is directly usable by the body and plays a central role in methylation, neurotransmitter production, and DNA synthesis. This formula supports healthy homocysteine metabolism, cardiovascular health, and fetal neural development during pregnancy when used under practitioner guidance. Thorne is known for its rigorous testing and hypoallergenic formulations, making this a trusted option for those needing higher-dose methylated folate. The product is free of gluten, dairy, and soy and designed for optimal absorption.

Benefits

  • Provides the active methylated form of folate (5-MTHF) for individuals with MTHFR polymorphisms
  • Supports healthy homocysteine levels and overall cardiovascular health
  • Promotes normal neurotransmitter synthesis for mood and cognitive support
  • Supports DNA synthesis and cell division, important for fetal neural development during pregnancy
  • Offers a highly purified, hypoallergenic formula suitable for sensitive individuals

Suggested Use

Take 1 capsule one to two times daily, or as recommended by your health professional.

Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FAQs

Q: Can I take Thorne 5-MTHF if I have an MTHFR gene mutation?
A: Yes. This product provides folate in the active 5-MTHF form, which bypasses the MTHFR enzymatic conversion step and is often recommended for individuals with MTHFR polymorphisms, under the guidance of a health professional.

Q: Is this product safe to use during pregnancy?
A: 5-MTHF is an important form of folate for fetal neural development, but the 5 mg dose is higher than standard prenatal folate amounts. Pregnant or nursing women should use this product only under the supervision of their healthcare practitioner.

Q: Should I take 5-MTHF with food or on an empty stomach?
A: It can be taken with or without food; however, many individuals prefer to take it with a meal to support comfortable digestion and to coordinate with other daily supplements.

Sign in to purchase

Purchasing is available to registered account holders. Create a free account or log in to continue — members automatically receive member pricing at checkout.

Log in → Create a free account

How to Purchase

  • Create Free Account
  • View Pricing
  • Purchase

Clear member and non-member pricing on every product

Cancel anytime — no long-term contracts

Questions? Contact us

These statements have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure, or prevent any disease. Root Cost Meds provides access to wellness education, supplement resources, and pharmacist-guided support. Information on this website is for educational and informational purposes only.